Acute Promyelocytic Leukemia

Not Verified
This information is AI generated and has not yet been reviewed by a specialist physician. AI can make mistakes

Disease overview

A blood cancer characterized by a marked increase in a type of immature white blood cells known as promyelocytes.

Common symptoms

Fatiguepallorinfections and increased risk of bleeding and bruising. [ ]

WHEN TO SUSPECT

  • Recommendation 1

    A combination of patient history, physical examination and numerous laboratory tests.

HOW TO TEST

  • Recommendation 1

    A combination of patient history, physical examination and numerous laboratory tests.

TREATMENT

  • Recommendation 1

    Centered on all-trans retinoic acid (ATRA
  • Recommendation 2

    tretinoin) and treatment is constituted of three phases
  • Recommendation 3

    induction, consolidation, and maintenance.

PRIMARY CARE

  • Recommendation 1

    ATRA alone is often used for maintenance, although it might be combined with chemotherapy agents.

FURTHER SUPPORT

  • Recommendation 1

    ~ 250 US-based physicans . Referral to Medical Genetics Department, if available. Initial virtual care is also available through organizations like TeleRare Health.

CLINICAL TRIALS

  • Recommendation 1

    ~ 1,200 trials

Sources

No data available

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