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| Disease found: | Acute Promyelocytic Leukemia |
| Current as of: | October 8, 2024 |
| Disease Overview: | A blood cancer characterized by a marked increase in a type of immature white blood cells known as promyelocytes. [more info] |
| Signs and Symptoms: | Fatigue, pallor, infections and increased risk of bleeding and bruising. [more info] |
| Diagnosis: | A combination of patient history, physical examination and numerous laboratory tests. [more info] |
| Treatment: | Centered on all-trans retinoic acid (ATRA; tretinoin) and treatment is constituted of three phases: induction, consolidation, and maintenance. [more info] |
| Clinical Management: | ATRA alone is often used for maintenance, although it might be combined with chemotherapy agents. [more info] |
| Referral: | ~ 250 US-based physicans [more info]. Referral to Medical Genetics Department, if available. Initial virtual care is also available through organizations like TeleRare Health. |
| Clinical Trials: | ~ 1,200 trials [more info] |