Acute Promyelocytic Leukemia

Not yet reviewed

This information is AI generated and has not yet been reviewed by a specialist physician. AI can make mistakes.

Disease overview

A blood cancer characterized by a marked increase in a type of immature white blood cells known as promyelocytes.

Common symptoms

Fatiguepallorinfections and increased risk of bleeding and bruising. [ ]

When to suspect

  • Recommendation 1

    A combination of patient history, physical examination and numerous laboratory tests.

How to test

  • Recommendation 1

    A combination of patient history, physical examination and numerous laboratory tests.

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Treatment

  • Recommendation 1

    Centered on all-trans retinoic acid (ATRA

  • Recommendation 2

    tretinoin) and treatment is constituted of three phases

  • Recommendation 3

    induction, consolidation, and maintenance.

Primary care

  • Recommendation 1

    ATRA alone is often used for maintenance, although it might be combined with chemotherapy agents.

Further support

  • Recommendation 1

    ~ 250 US-based physicans . Referral to Medical Genetics Department, if available. Initial virtual care is also available through organizations like TeleRare Health.

Clinical trials

Clinical Trials

Sources

No data available

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