Primary care
Recommendation 1
The causative drug needs to be avoided indefinitely.
DReSS Syndrome
Not yet reviewedThis information is AI generated and has not yet been reviewed by a specialist physician. AI can make mistakes.
Disease overview
A rare disorder that can affect the skin, blood and any internal organs, most commonly the liver, kidney, lungs and heart. The cause of DReSS is multifactorial involving drug-exposure, genetic predisposition, viral reactivation and immune system responses.
Common symptoms
Most common are a flu-like prodrome of malaisesore throatfever and swollen lymph nodes. Followed by maculopapular or morbilliformurticated papular rashes and full body redness with exfoliative erythroderma. [ ]
When to suspect
Recommendation 1
The RegiSCAR criteria (Kardaun et al. 2007) and The Japanese Consensus Group criteria (Shiohara et al. 2007).
How to test
Recommendation 1
The RegiSCAR criteria (Kardaun et al. 2007) and The Japanese Consensus Group criteria (Shiohara et al. 2007).
ZebraMD is partnering with Ambry Genetics for clinical-grade whole genome testing for rare diseases. Ambry accepts insurance. If you don’t have a physician to order this test, join our referral list and our team will reach out.
Treatment
Recommendation 1
Systemic steroids alongside identification and immediate withdrawal the culprit drug.
Further support
Recommendation 1
Aziz, Mariam MD and Ishmael, Faoud MD . Referral to Medical Genetics Department, if available. Initial virtual care is also available through organizations like TeleRare Health.
Clinical trials
Clinical Trials
Sources
No data available
Interested in learning more about DReSS Syndrome?
Follow to receive regular updates to the latest research development on this disease via email newsletter.