Primary care
Recommendation 1
Ankle or foot surgery or special shoes with good ankle support, acetaminophen and NSAIDs for muscle pain, gabapentin or carbamazepine for nerve pain
Dejerine-Sottas Syndrome
Not yet reviewedThis information is AI generated and has not yet been reviewed by a specialist physician. AI can make mistakes.
Disease overview
Inherited disorder that progressively affects the peripheral nerves, hindering the body's ability to move
Common symptoms
Often begins suddenly at age 2 with tinglingpricklingor burningas well as muscle weakness that starts in the back of the leg and moves to the front. Delayed motor milestonesmild vision difficultiespainloss of heat sensitivityatrophy of leg musclesataxiascoliosis
When to suspect
Recommendation 1
Genetic testing or criteria for a clinical diagnosisRecommendation 2
Symptoms beginning by age two with delayed motor milestones, Severe motor and sensory impact, Motor nerve conduction velocity is greatly lowered, Nerve biopsy shows loss of myelin
How to test
Recommendation 1
Genetic testing or criteria for a clinical diagnosisRecommendation 2
Symptoms beginning by age two with delayed motor milestones, Severe motor and sensory impact, Motor nerve conduction velocity is greatly lowered, Nerve biopsy shows loss of myelin
ZebraMD is partnering with Ambry Genetics for clinical-grade whole genome testing for rare diseases. Ambry accepts insurance. If you don’t have a physician to order this test, join our referral list and our team will reach out.
Treatment
Recommendation 1
Supportive
Further support
Recommendation 1
Neurologists, physiatrists, orthopedic surgeons, PT, OT. Referral to Medical Genetics Department, if available. Initial virtual care is also available through organizations like TeleRare Health.
Clinical trials
Clinical Trials
Sources
No data available
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