PRIMARY CARE
Recommendation 1
Treatment is usually reserved for those with a history of bleeding or prior to surgeries or dental procedures. Regular monitoring of Factor XI levels.
Factor XI deficiency
Not Verified
Disease overview
rare bleeding disorder-deficiency of coagulation Factor XI impairs blood clotting process.
Common symptoms
prolonged bleeding after injuriessurgeriesproceduresmenstrual bleedingspontaneous bleeding (less common)
WHEN TO SUSPECT
Recommendation 1
Specific blood tests to measure Factor XI levels and assess the clotting function
HOW TO TEST
Recommendation 1
Specific blood tests to measure Factor XI levels and assess the clotting function
TREATMENT
Recommendation 1
PreventativeRecommendation 2
recombinant factor XI replacement. AcuteRecommendation 3
TXA for minor bleeds, FFP for more significant bleeds
FURTHER SUPPORT
Recommendation 1
Center for Blood Disorders, Weill Cornell Medicine, and other treatment centers for hemophilia. Referral to Medical Genetics Department, if available. Initial virtual care is also available through organizations like TeleRare Health.
CLINICAL TRIALS
Recommendation 1
None are available, but can sign up to be notified when one becomes available
Sources
No data available
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