Sheehan Syndrome

Not yet reviewed

This information is AI generated and has not yet been reviewed by a specialist physician. AI can make mistakes.

Disease overview

postpartum hypopituitarism; hypotension following postpartum hemorrhage causing ischemic pituitary necrosis

Common symptoms

Symptoms related to low pituitary hormones: failure to lactate (common)failure to resume regular mensesexcessive fatigueadrenal crisis. Symptoms may appear acutely or months-years after delivery.

When to suspect

  • Recommendation 1

    Standard blood tests for pituitary hormone levels. Head CT/MRI will likely show empty sella

  • Recommendation 2

    also rules out tumor.

How to test

  • Recommendation 1

    Standard blood tests for pituitary hormone levels. Head CT/MRI will likely show empty sella

  • Recommendation 2

    also rules out tumor.

ZebraMD is partnering with Ambry Genetics for clinical-grade whole genome testing for rare diseases. Ambry accepts insurance. If you don’t have a physician to order this test, join our referral list and our team will reach out.

Treatment

  • Recommendation 1

    Pituitary hormone replacement therapy as needed based on patient-specific deficiencies.

Primary care

  • Recommendation 1

    Long-term endocrinology support. Patients who desire additional children may need fertility assistance. Support group

  • Recommendation 2

    Maternal Pituitary Support

Further support

  • Recommendation 1

    Managed by Endocrinology. Referral to Medical Genetics Department, if available. Initial virtual care is also available through organizations like TeleRare Health.

Clinical trials

Clinical Trials

Sources

No data available

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